17
May

How to Use the Gedmatch Genesis One to One Tool

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Do you want to know how to use the Gedmatch Genesis One to One comparison tool? This tool is one of the most useful tools on the site, and in this post, I’ll teach you all about using it.

Most people find their way to the One-to-One tool after they have found an interesting match on the One-to-Many comparison tool and would like to examine the match more closely.

In the article below, you’ll learn:

  • What you can learn from the Gedmatch Genesis One-to-One tool
  • How to use the Gedmatch Genesis One-to-One tool
  • How to understand the Gedmatch Genesis One-to-One results
  • How to adjust the tool settings

What can you learn from the Gedmatch Genesis One to One tool?

I have two favorite tools on Gedmatch Genesis. The One-to-Many tool makes the list, naturally, but I absolutely LOVE being able to compare my DNA with that of my DNA matches using the One-to-One tool.

What does the One-to-One tool tell you?

The Gedmatch Genesis One-to-One tool compares your DNA with that of another Gedmatch Genesis user. If the software detects matching DNA segments between you and the other user, the segments will be listed on the results.

The information that we can learn from this tool can help us learn how closely related we might be to our matches and solve difficult family tree mysteries.

For example, if we share many small segments with a DNA match, it could indicate being related in a few different ways. Longer segments could point towards a more recent ancestor.

The ways in which the tool can help you with your genetic genealogy research are extensive!

Just a few of the specific details Gedmatch Genesis One to One tool can tell you:

  • The total number of centimorgans that you share with your match
  • The exact location on your chromosomes where you can find DNA segments shared with your match
  • The estimated distance to your most recent common ancestor

How to use the Gedmatch Genesis One-to-One tool

The instructions below will help you get started using the One-to-One tool, but you will first need to log in to your Gedmatch Genesis account.

You can access the Gedmatch Genesis login page by clicking on the link below:

Gedmatch Genesis login

From your Gedmatch Genesis dashboard, which is the screen that you see once you have logged in to your account, you can find the One-to-One tool towards the right side of your screen under the “DNA Applications” heading.

In the image below, I have highlighted the One-to-One tool in red so you’ll know exactly which tool we are learning about for this post:

How to access the gedmatch genesis one to one tool to compare your DNA with that of your DNA matches
This image shows you exactly where to click to access the Gedmatch Genesis One-to-One tool. This tool allows you to compare your DNA with the DNA of a specific DNA match, as long as you have both uploaded your DNA to Gedmatch Genesis.

Which information to enter in the One-to-One tool

Once you have opened up the Gedmatch Genesis One-to-One tool, you’ll need to enter some information into some of the fields to get the tool to work.

You must enter:

  • your kit number
  • the kit number of the person that you’d like to compare with yours

The tool has several default settings, so it isn’t necessary to change any of the other fields.

When I run the tool, I typically leave most of the fields as-is, but I do prefer to receive the results as a list. The default results setting is “Graphics and Position.”.

To me, the results are easier to understand in the “Position Only” form. In the image below, you can see how to choose to receive your results in the “Position Only” form, too.

Highlighted in red is the option that you should choose in order to see only the matching DNA segments start and end positions. The default seeing (Graphics and Positions) will display the corresponding chromosome and visually display the matching segment along with the position.

Once you have entered in your kit number as well as decided whether you would like the tool to display the results as “Graphics and Position” or “Position Only”, you can scroll to the bottom of the page and press the “Submit” button.

How to understand the Gedmatch Genesis One-to-One results

After you have submitted the required information on the tool page, you will be able to view the results of the comparison.

If you have NO matching DNA segments, you will see a message that says “No shared DNA segments found “. If you chose to display both the graphics and the position, this message will appear at the very bottom (you’ll have to scroll down to see it).

If you do have matching DNA segments with your match, you will receive results that look something like a spreadsheet table.

You might share only one DNA segment with your match, or several DNA segments, as show in the image below:

This is an example of Gedmatch Genesis One-to-Many results. Instructions about how to understand these results are found in this section of the article.
This is an example of Gedmatch Genesis One-to-Many results. Instructions about how to understand these results are found in this section of the article.

Meanings of the columns on Gedmatch Genesis tools

At first glance, you might think the results are too scientific and technical to understand. Trust me, if I can do it, you can do it!

  • The first column of the results tells you the number of chromosome where you can find the matching segment.
  • The second column displays the exact location of beginning of the DNA segment
  • The third column tells you the exact location of the end of the DNA segment
  • The fourth column (centimorgans) tells you exactly how long the DNA segment is
  • The final column tells you how many SNPs were tested to measure the segment

Each person has 22 numbered chromosomes. I can see in the results above that the two people that I compared share 12 DNA segments on 10 of their 22 chromosomes.

At the very bottom of the One-to-One results, I can see a “summary” of the results, if you will.

Gedmatch Genesis explains that these two users have:

  • A largest shared DNA segment of 34.9 cMs
  • 158.8 cMs of shared DNA (of combined segments above 7 cMs in length)
  • An estimated distance to most recent common ancestor of 3.2 generations

In order to really understand how these two individuals are related, I will need to inspect (and possibly even build) their family trees back far enough to spot their common ancestor(s).

Tool settings for Gedmatch Genesis One-to-One comparison

There are several tool settings that we can adjust in order to learn even more from the Gedmatch Genesis One-to-One comparison tool.

Why would you want to see the Graphics comparison on Gedmatch Genesis?

We already discussed the Position Only vs. Graphics and Position option above, but I didn’t explain why you might want to see the graphics on your results.

In cases where you are closely related to a match (i.e. a sibling), you might be interested in comparing half-identical regions to full identical regions. These different regions are indicated on your Gedmatch Genesis tool results by the color-coded key near the top of the results page.

What’s the difference between a fully identical region and a half-identical region?

Above, I mentioned that everyone has 22 numbered chromosomes. What I didn’t say is that we actually have two copies of each chromosome.

We inherited one copy of each chromosome from each of our parents equaling about 50% of their DNA.

Our siblings also inherited 50% of our parents’ DNA, but it won’t be the exact same 50% that we inherited. Some will be identical, and overlap in “fully indentical regions”, meaning regions that match DNA inherited from both mom and dad.

Most of our DNA matches will only share “half-identical” regions with us because they are only related on one side of our family.

How to adjust the segment size threshold on the Gedmatch Genesis One-to-One tool

By default, the Gedmatch Genesis One-to-One comparison tool only displays DNA segments that are larger than 7 cMs in length. This is what you might call the “industry standard” of genetic genealogy.

The smaller the DNA segment, the higher the probability that the DNA segment is a false positive (identical by state) instead of a DNA segment inherited from a shared common ancestor.

The result of this is that you can feel relatively confident (it’s all relative, right?) that most of the DNA segments that you share with your match are probably identical by descent.

By having a lower threshold of 7-8 cMs, testing companies (and Gedmatch Genesis) strike a nice balance between eliminating a good amount of false positives and providing us with enough information to learn as much as we can (or want to) about our family tree.

With all of this said, there are still some valid reasons that you might want to lower the threshold when you compare your DNA with that of your match.

Keeping in mind that more than 99% of segments as small as 3 cMs are going to be false positives, I lowered the threshold so you can see what the results look comparing the same individuals that I showed you above:

When you lower the Gedmatch Genesis One to One comparison tool threshold to display segments larger than 3 cMs, lots of small segments might show up
This image shows what happened when I lowered the threshold to 3 cMs for the same two individuals that I compared at 7 cMs in the beginning of this post. Lots of small segments showed up – some are likely false, but others might not be.

There were 62 DNA segments found at the 3 cM threshold or larger. Some of these segments were as small as 3.0, but others were as large as 6.7. The rest fell somewhere in-between.

The two people whose DNA I compared for this example are from the same town where their families have lived for many, many, many generations. Many, but not all, of these very small segments might be “true” matches.

Conclusion

I hope that this post has helped you understand more about how to use the Gedmatch Genesis One-to-One tool, how to understand the results, how to adjust the tool settings.

If you have any questions about something that you read in this post, or if you would like to share your own experience using this tool, I would love to hear from you in the discussion below.

Thanks for being here today!

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How to Use the Gedmatch Genesis One to One Tool
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How to Use the Gedmatch Genesis One to One Tool
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Want to know how to use the Gedmatch Genesis One to One comparison tool? It's one of the most useful tools on the site and I'll teach you how to use it.
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